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Incredible Health Benefits of Jiaogulan (Proven)

Incredible Health Benefits of Jiaogulan (Proven).

Jiaogulan or Gynostemma Pentaphyllum is a climbing vine also known as an immortality herb as it has multiple rejuvenation properties and other health benefits.

It's a climbing vine that's believed to promote a healthy and long life. The plant grows extensively in the mountain region of Southern China.

Its leaves are typically used in Traditional Chinese Medicine (TCM). It's used as a substitute for Ginseng. In modern times, fruits are also used to prepare medicine in China, Japan, and some other countries.

Jiaogulan is included in TCM during the last decade but it has a long history of folk use in the Guizhou province of China.

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Apart from the use of alternative medicines, the herb is used as a functional food in many countries. 

The leaves of Jiaogulan are considered a powerful adaptogen similar to ginseng.  

This medicinal herb is used in many forms like tea, powder, tablets, and capsules.

The earliest documentation of Gynostemma Pentaphyllum was made in China in Ming Dynasty.

The plant was described by a Chines Physician Zhu Xiao over 600 years ago in his book Materia Medica for Famine

But its use as a medicine was recorded first by Li Shizhen in his book ''Compendium of Materia Medica'' published in 1578. 

The medicines prepared from Gynostemma Pentaphyllum are used to treat ailments as well as to prevent diseases.

Health Benefits of Jiaogulan

Jiaogulan and Gynostemma Pentaphyllum are two popular names of this vine. But there are several other names used worldwide. 

Table of Contents

  • Various Names of Jiaogulan
  • Chemical Constituents of Gynostemma Pentaphyllum
  • Important Facts of Gynostemma
  • Availability of Gynostemma Pentaphyllum
  • Is Jiaogulan a Green Tea
  • Why Jiaogulan is called Southern Ginseng?
  • Use of Gynostemma Pentaphyllum
  • Limitations
  • Toxicity and Safety
  • Who Should not Use Jiagulan?
  • Tiens Cell Rejuvenation Capsules with Gynostemma Pentaphyllum
  • My Suggestion
  • Final Thoughts

Various Names of Jiaogulan

The scientific name of Jiaogulan is Gynostemma pentaphyllum (Thunb.) Makino.The other names Jiaogulan include the following:

  • Gynostemma Pentaphyllum,
  • Miracle Grass,
  • Poor man's Ginseng, 
  • Five-leaf Ginseng,
  • Southern ginseng,
  • Fairy herb, 
  • Gospel Herb,
  • and more.

Chemical Constituents of Gynostemma Pentaphyllum

Constituents of the Jiaogulan plant include:
sterols, chlorophyll, flavonoids, gypenosides, saponin. Studies on its chemical constituent show-

33 new dammarane glycosides, together with 9 known compounds, gypenosides IV, VIII, XLVIII, XLIX, LXIX, LXXI, gylongiposide I, allantion, and vitexin were isolated from the methanol extract of the aerial parts of this medicinal plant.

Important Facts of Gynostemma 

  • It belongs to the genus Gynostemma and comes from the family of cucumbers or guards.
  • One of the interesting features is each plant exists either as male or female. Eventually, to get seeds, both a male and female plant must be grown.
  • Gynostemma Pentaphyllum tea is the only tea that contains no caffeine.
  • Jiaogulan is a natural alternative sweetener.
  • In Japan, Gynostemma is known as Amachazuru meaning the sweet tea vine.
  • The aged people Guizhou province of China use this immortality herb regularly as they believe that the herb can increase longevity.

Availability of Gynostemma Pentaphyllum

Gynostemma Pentaphyllum is mostly grown in China, Japan, Korea, India, Bangladesh, and some other Asian Countries. 

In China, the plant usually grows along the slopes of mountains at an altitude of 300-3,200 meters above sea level. Besides, it also grows in different forests of China.

Several products in multiple forms made from Jiaogulan are now available in the USA, China, India, and many other Asian and European countries.

Is Jiaogulan a Green Tea 

Yes, it's a kind of green tea. The plant is known as the sweet tea vine. The taste of Jiaogulan leaf is bittersweet. It's a natural, caffeine-free green tea.

Why Jiaogulan is called Southern Ginseng?

Typically, saponin compounds of Jiaogulan are identical to those found in most ginseng roots. 

Evidence indicates that Jiagulan may complement Panax ginseng because of the presence of a high ginsenoside content in it.
Thus, it's used as a substitute for ginseng, although some other active compounds of ginseng are not present in Jiaogulan.

Furthermore, this miracle herb grows extensively in Southern China. These are the main reasons why it is called Southern Ginseng.

How to Extract & Purify Jiaogulan 

You need to know that Gynostemma Pentaphyllum polysaccharides are structural components of cell walls.

The extraction methods are used that can break down the cell wall from both the outer and inner layers without affecting the structural morphology of the cell wall.
There are several methods of extractions and purification of Gynostemma Pentaphyllum. 

The most common conventional method of extraction is the hot water method. This method of extraction involves high temperature and a long time.

The temperature, time used for extraction, and liquid to solid ratio are some factors that can influence the yield.

But nowadays, modern methods with higher efficiency like ultrasonic or microwave-assisted extraction are used to maximize the yield.

After extraction, crude Jiagulan is processed for purification using different techniques.

Use of Gynostemma Pentaphyllum

Gynostemma Pentaphyllum is extensively used as a functional food. It is also used as an alternative medicine for the prevention treatment of several conditions. 

The health supplements made from Jiaogulan include biscuits, noodles, tea, beer, and other liquid beverages.

The Impact of Jiaogulan on Your Health

Now, I'm going to present the health benefits or efficacies of Gynostemma Pentaphyllum. Jiaogulan is claimed to be effective in dozens of conditions. 

In the recent past, various studies have reported many functions of Jiaogulan. These include antioxidant, antimicrobial, anticancer, antiaging, antifatigue, antiinflammation, hypolipidemic, neuroprotective, and immune-boosting activities.

Jiaogulan is extensively used in Chinese medicines for treating several diseases, including cardiovascular diseases, diabetes, hepatitis, and cancer.

Truly speaking, evidence to support the claims is insufficient in most cases. For some conditions, the research and clinical trials are old. 

So, I'd like to share them in two groups - the group of conditions supported by strong evidence and the group of conditions with insufficient evidence.

Evidence-Based Health Benefits of Jiaogulan

Boost Immunity

Jiaogulan is used for boosting the immune system and leading a disease-free and healthy life.

People with anti-immune or autoimmune conditions should avoid using this herb. 


Several studies on animals show that Gynostemma Pentaphyllum can reduce the blood sugar level significantly. So, it can help control diabetes, especially type 2.

A study shows an instant improvement of glycemia and insulin sensitivity. It concludes that using Gynostemma pentaphyllum tea to treat type 2 diabetic patients is an effective and safe approach.

Patients using medicines for reducing blood sugar levels should intake Jiaogulan with caution.

Weight Management 

According to WOODRUFF LAB, a vast majority of American adults will suffer from obesity and over 50% will suffer from diabetes and prediabetic condition in 2020. 

Obesity is a common problem of human health across the globe. 2 years ago, In the US, 39.6% of adults and 18.5% of children (ages 2-19) are obese.  

Obese people have a Body Mass Index (BMI) of 30 or more and in the case of overweight, the BMI is 25 or more.  

Obesity may cause type 2 diabetes, heart disease, stroke, and certain types of cancers.

An effective weight management program is essential to get rid of overweight and obesity. Health experts usually recommend diet and exercise for reducing the overweight.

Jiaogulan may help obese people to reduce weight. Jiaogulan leaf extract can reduce abdominal fat significantly. Studies in mouse obesity models produce great results without adverse symptoms.

A study shows that gypenosides from Jiaogulan tea can reduce overweight and insulin resistance.

Prevention of Cancer

In TCM, Jiaogulan is considered to have an anti-cancer effect and thus widely used for the prevention and treatment of cancer.

The results of several clinical studies have indicated that Jiaogulan could have potent curative effects on cancer

Several mechanisms of action have been proposed regarding the anti-cancer activities of Jiaogulan

These include cell cycle arrest, apoptosis, inhibition of invasion and metastasis, inhibition of glycolysis, and immunomodulating activities.

Reduce Cholesterol

A waxy and fat-like substance found in your cells is known as cholesterol. Your body needs it to make vitamin D and hormones. 

It also helps to digest the food you intake. But excessive cholesterol in your blood can form plaque (atherosclerosis) that can lead to coronary artery diseases.

Is cholesterol good or bad for your health?  

Some cholesterol is ''good'' but excessive is always bad. 

Most of you are familiar with the terms HDL, LDL, VLDL. These are different types of cholesterol, known as lipoproteins (lipd+protein).

  • HDL
HDL or high-density lipoprotein is known as good cholesterol. It carries cholesterol from different parts of your body and sends it back to the liver. Ultimately liver removes it from your body.
  • LDL
LDL or low-density lipoprotein is known as bad cholesterol as it carries cholesterol that builds plaque in the arteries. 
  • VLDL
VLDL or very-low-density lipoprotein is also known as bad as carries triglycerides and responsible for to build of plaque in the arteries. 

So maintaining a normal cholesterol level can help protect your heart. Intake of Jiagulan can reduce the total cholesterol and increase the high-density lipoprotein (HDL). 

Studies have shown that this herb help to reduce bad cholesterol (LDL) and increase (HDL). This helps to maintain the normal range.

Twenty papers have been published on this topic with efficacies ranging from 67%-93%.

Stress Management

Long-term or chronic stress is harmful to your health, both mental health and physical health. 

Chronic stress can cause several health problems, including anxiety, depression, cardiovascular disorders, and diabetes.

As an adaptogenic herb, it can reduce stress. An animal-based study shows that herbal ethanol extracts of Jiaogulan are effective in reducing stress-related anxiety disorders.

Effects on the Health Conditions Lacking Evidence

To draw a conclusion about the therapeutic effects of Jiaogulan on the following conditions, adequate studies are needed:

Constipation, Gallstones, Hypertension, Insomnia, Bronchitis, Stomach ulcers, and more. 

So before deciding to intake Jiagulan to treat any of these conditions, you must consult your physician.


Inadequate clinical studies have been conducted to support therapeutic effects.
There is a lack of dosing information.

While using Jiaogulan, the probability of adverse symptoms like nausea and frequent bowel movement is there.

Toxicity and Safety

Jiagulan is considered safe and no toxicity is reported yet. But the symptoms of nausea and increased bowel movement may be observed.

Who Should not Use Jiagulan? 

  • Pregnant and breastfeeding women
  • People with diabetes who are using insulin or under medication
  • People with autoimmune diseases.

Tiens Cell Rejuvenation Capsules with Gynostemma Pentaphyllum 

Please read the affiliate disclosure as this section contains a sponsored link. 

If you decide to buy it you need an id number, you can use mine to get a discount. My id number is 88307164 which is valid all over the world.

The Giant Direct Selling Company Tiens produces several high-quality dietary supplements and distributes them in 190 countries.


I have been acquainted with Tiens Cell Rejuvenation Capsules for over 17 years. In addition to using it personally, I have been involved with its marketing for almost a decade and a half.

Tiens cell rejuvenation capsules are made based on Traditional Chinese Medicine (TCM). 

This food supplement is specially made to increase the efficiency of our body and maintain the balance of yin and yang energy.

It helps improve the body's immunity system and improves the functioning of our body's energy system, cardiovascular system, and circulatory system.

In some countries, this product is known as Tiens Jiagulan.

It contains 4 antioxidants aimed at keeping our heart and circulatory system healthy.

Apart from Gynostemma pentaphyllum, it contains carrot root powder, polyphenol, and vitamin C.

All ingredients used in these products are rich in vitamins, minerals, and several bioactive compounds.

Tiens Jiaogulan/ Cell Rejuvenation is claimed to be effective in:

  • Helps in reducing the contents of harmful lipid in blood & strengthens the cardiovascular system
  • Improves body's blood circulation
  • Helps in lowering blood sugar level
  • Provides herbal support to the body
  • Helps in activating metabolism
  • Helps Prevent fat accumulation 
  • Remove toxic substances from your body
  • Strengthens the immune system
  • As a strong antioxidant, it helps remove free radicals
  • Delays age-related degeneration
  • Improves oxygen uptake in a low oxygen environment
  • Helps in improving your vision 
  • Acts as a blood purifier
  • Reduces bad cholesterol i.e low-density lipoprotein (LDL)
  • Protects from stress and fatigue.

My Suggestion

If you want to use Jiaogulan for the prevention or treatment of any disease, consult your doctor or a registered practitioner of alternative medicine.

Final Thoughts

Jeogulan is one of the many resources that nature has given us. More research and evidence are needed to encourage its more and more use to protect human health. 

We look forward to using this Immortality Herb for best use in human health.

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